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Case Files
™
Biochemistry
Second Edition
EUGENE C.TOY, MD
The John S. Dunn Senior Academic Chief and Program
Director
Obstetrics and Gynecology Residency Program
The Methodist Hospital, Houston
Clerkship Director and Clinical Associate Professor
Department of Obstetrics and Gynecology
University of Texas Medical School at Houston
Houston,Texas
WILLIAM E. SEIFERT, JR., PHD
Senior Lecturer and Medical Biochemistry Course
Director
Department of Biochemistry and Molecular Biology
University of Texas Medical School at Houston
Houston,Texas
HENRY W. STROBEL, PHD
Professor
Department of Biochemistry and Molecular Biology
Assistant Dean For Student Affairs
Associate Dean for Faculty Affairs
University of Texas Medical School at Houston
Houston,Texas
KONRAD P. HARMS, MD
Clinical Assistant Professor
Weill Cornell College of Medicine
Associate Program Director
Obstetrics and Gynecology Residency
The Methodist Hospital, Houston
Houston,Texas
New York Chicago San Francisco
Lisbon London Madrid Mexico City
Milan New Delhi San Juan Seoul
Singapore Sydney Toronto
Copyright © 2008 by The McGraw-Hill Companies, Inc. All rights reserved. Manufactured in the
United States of America. Except as permitted under the United States Copyright Act of 1976, no
part of this publication may be reproduced or distributed in any form or by any means, or stored
in a database or retrieval system, without the prior written permission of the publisher.
0-07-164309-5
The material in this eBook also appears in the print version of this title: 0-07-148665-8.
All trademarks are trademarks of their respective owners. Rather than put a trademark
symbol after every occurrence of a trademarked name, we use names in an editorial fashion only,
and to the benefit of the trademark owner, with no intention of infringement of the trademark.
Where such designations appear in this book, they have been printed with initial caps.
McGraw-Hill eBooks are available at special quantity discounts to use as premiums and sales
promotions, or for use in corporate training programs. For more information, please contact
George Hoare, Special Sales, at george_hoare@mcgraw-hill.com or (212) 904-4069.
TERMS OF USE
This is a copyrighted work and The McGraw-Hill Companies, Inc. (“McGraw-Hill”) and its
licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as
permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work,
you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works
based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it
without McGraw-Hill’s prior consent. You may use the work for your own noncommercial and
personal use; any other use of the work is strictly prohibited. Your right to use the work may be
terminated if you fail to comply with these terms.
THE WORK IS PROVIDED “AS IS.” McGRAW-HILL AND ITS LICENSORS MAKE NO
GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR COMPLETE-
NESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY
INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR
OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS OR IMPLIED,
INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY
OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill and its licensors do not warrant
or guarantee that the functions contained in the work will meet your requirements or that its
operation will be uninterrupted or error free. Neither McGraw-Hill nor its licensors shall be liable
to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for
any damages resulting therefrom. McGraw-Hill has no responsibility for the content of any
information accessed through the work. Under no circumstances shall McGraw-Hill and/or its
licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages
that result from the use of or inability to use the work, even if any of them has been advised of the
possibility of such damages. This limitation of liability shall apply to any claim or cause
whatsoever whether such claim or cause arises in contract, tort or otherwise.
DOI: 10.1036/0071486658
❖
DEDICATION
To my friend, mentor, and role model, Dr. Benton Baker III,
who taught me by his example, the importance of integrity, unselfishness,
and teamwork.
—
ECT
To my wife, Heidi, and to Koen and Kort,
for their unwavering love and support and
for reminding me daily of what is really important in life.
—
KPH
To Dr. John A. DeMoss, Founding Chair of the Department of Biochemistry
and Molecular Biology of the University of Texas Medical School at Houston.
Dr. DeMoss served as Department Chair from 1971 until
he stepped down from that office in 1992, serving as Professor until 2001
when he became Emeritus Professor, his present position. Dr. DeMoss is that
unique kind of scholar who excels at both research and teaching. He loves
teaching and he is gifted at it. Dr. DeMoss not only has taught and
continues to teach generations of students, he also teaches faculty,
especially young faculty, how to teach and to love teaching. It is therefore
in gratitude for his teaching of us that we dedicate this book to
Dr. John A. DeMoss.
—
WES
&
HWS
Copyright © 2008 by The McGraw-Hill Companies, Inc. Click here for terms of use.
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Case Files
™
Biochemistry
Second Edition
EUGENE C.TOY, MD
The John S. Dunn Senior Academic Chief and Program
Director
Obstetrics and Gynecology Residency Program
The Methodist Hospital, Houston
Clerkship Director and Clinical Associate Professor
Department of Obstetrics and Gynecology
University of Texas Medical School at Houston
Houston,Texas
WILLIAM E. SEIFERT, JR., PHD
Senior Lecturer and Medical Biochemistry Course
Director
Department of Biochemistry and Molecular Biology
University of Texas Medical School at Houston
Houston,Texas
HENRY W. STROBEL, PHD
Professor
Department of Biochemistry and Molecular Biology
Assistant Dean For Student Affairs
Associate Dean for Faculty Affairs
University of Texas Medical School at Houston
Houston,Texas
KONRAD P. HARMS, MD
Clinical Assistant Professor
Weill Cornell College of Medicine
Associate Program Director
Obstetrics and Gynecology Residency
The Methodist Hospital, Houston
Houston,Texas
New York Chicago San Francisco
Lisbon London Madrid Mexico City
Milan New Delhi San Juan Seoul
Singapore Sydney Toronto
Copyright © 2008 by The McGraw-Hill Companies, Inc. All rights reserved. Manufactured in the
United States of America. Except as permitted under the United States Copyright Act of 1976, no
part of this publication may be reproduced or distributed in any form or by any means, or stored
in a database or retrieval system, without the prior written permission of the publisher.
0-07-164309-5
The material in this eBook also appears in the print version of this title: 0-07-148665-8.
All trademarks are trademarks of their respective owners. Rather than put a trademark
symbol after every occurrence of a trademarked name, we use names in an editorial fashion only,
and to the benefit of the trademark owner, with no intention of infringement of the trademark.
Where such designations appear in this book, they have been printed with initial caps.
McGraw-Hill eBooks are available at special quantity discounts to use as premiums and sales
promotions, or for use in corporate training programs. For more information, please contact
George Hoare, Special Sales, at george_hoare@mcgraw-hill.com or (212) 904-4069.
TERMS OF USE
This is a copyrighted work and The McGraw-Hill Companies, Inc. (“McGraw-Hill”) and its
licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as
permitted under the Copyright Act of 1976 and the right to store and retrieve one copy of the work,
you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works
based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part of it
without McGraw-Hill’s prior consent. You may use the work for your own noncommercial and
personal use; any other use of the work is strictly prohibited. Your right to use the work may be
terminated if you fail to comply with these terms.
THE WORK IS PROVIDED “AS IS.” McGRAW-HILL AND ITS LICENSORS MAKE NO
GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR COMPLETE-
NESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY
INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR
OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS OR IMPLIED,
INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY
OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill and its licensors do not warrant
or guarantee that the functions contained in the work will meet your requirements or that its
operation will be uninterrupted or error free. Neither McGraw-Hill nor its licensors shall be liable
to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for
any damages resulting therefrom. McGraw-Hill has no responsibility for the content of any
information accessed through the work. Under no circumstances shall McGraw-Hill and/or its
licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages
that result from the use of or inability to use the work, even if any of them has been advised of the
possibility of such damages. This limitation of liability shall apply to any claim or cause
whatsoever whether such claim or cause arises in contract, tort or otherwise.
DOI: 10.1036/0071486658
❖
DEDICATION
To my friend, mentor, and role model, Dr. Benton Baker III,
who taught me by his example, the importance of integrity, unselfishness,
and teamwork.
—
ECT
To my wife, Heidi, and to Koen and Kort,
for their unwavering love and support and
for reminding me daily of what is really important in life.
—
KPH
To Dr. John A. DeMoss, Founding Chair of the Department of Biochemistry
and Molecular Biology of the University of Texas Medical School at Houston.
Dr. DeMoss served as Department Chair from 1971 until
he stepped down from that office in 1992, serving as Professor until 2001
when he became Emeritus Professor, his present position. Dr. DeMoss is that
unique kind of scholar who excels at both research and teaching. He loves
teaching and he is gifted at it. Dr. DeMoss not only has taught and
continues to teach generations of students, he also teaches faculty,
especially young faculty, how to teach and to love teaching. It is therefore
in gratitude for his teaching of us that we dedicate this book to
Dr. John A. DeMoss.
—
WES
&
HWS
Copyright © 2008 by The McGraw-Hill Companies, Inc. Click here for terms of use.
This page intentionally left blank
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